Cheap flights from Quito to Santa Cruz
Cheapest current fares: $388 in December 2026 on connecting flights.
Cheapest month-by-month fares
Lowest available fare per calendar month from Quito (UIO) to Santa Cruz (VVI). Refreshed daily.
Quito (UIO) → Santa Cruz (VVI)
- December 2026 $388
- August 2026 $392
- September 2026 $411
Frequently asked questions
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What is the cheapest month to fly from Quito to Santa Cruz?
Based on current 6-month forward fare data, December 2026 is the cheapest month to fly from Quito (UIO) to Santa Cruz (VVI), with fares starting from $388.
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What is the lowest current fare from UIO to VVI?
The lowest currently-listed fare from Quito (UIO) to Santa Cruz (VVI) is $388 on 2026-12-03.
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Is there a direct flight from Quito to Santa Cruz?
There is currently no non-stop service from UIO to VVI. Most travellers connect through a hub airport. See our route page for current stopover options.
Related guides for this route
Sibling pages — full route detail, airport overviews, visa context, per-airline routes.