Flights from Des Moines to Charleston (DSM → CHS)

DSM
Des Moines
Des Moines International, USA
CHS
Charleston
Charleston Afb International, USA
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No direct flights found. Here are the 20 fastest 1-stop options.
viaNashville(BNA)
DSM→BNA+1h 30mBNA→CHS
3h 20m
viaCharlotte(CLT)
DSM→CLT+1h 30mCLT→CHS
3h 21m
viaAtlanta(ATL)
DSM→ATL+1h 30mATL→CHS
3h 24m
viaChicago(MDW)
DSM→MDW+1h 30mMDW→CHS
3h 30m
viaChicago(ORD)
DSM→ORD+1h 30mORD→CHS
3h 31m
viaDetroit(DTW)
DSM→DTW+1h 30mDTW→CHS
3h 46m
viaMinneapolis(MSP)
DSM→MSP+1h 30mMSP→CHS
4h
viaWashington(DCA)
DSM→DCA+1h 30mDCA→CHS
4h 3m
viaPhiladelphia(PHL)
DSM→PHL+1h 30mPHL→CHS
4h 23m
viaDallas(DFW)
DSM→DFW+1h 30mDFW→CHS
4h 33m
viaNew York(EWR)
DSM→EWR+1h 30mEWR→CHS
4h 36m
viaNew York(LGA)
DSM→LGA+1h 30mLGA→CHS
4h 40m
viaFort Myers(RSW)
DSM→RSW+1h 30mRSW→CHS
4h 42m
viaHouston(IAH)
DSM→IAH+1h 30mIAH→CHS
4h 46m
viaHouston(HOU)
DSM→HOU+1h 30mHOU→CHS
4h 49m
viaFort Lauderdale(FLL)
DSM→FLL+1h 30mFLL→CHS
4h 53m
viaMiami(MIA)
DSM→MIA+1h 30mMIA→CHS
4h 57m
viaAustin(AUS)
DSM→AUS+1h 30mAUS→CHS
5h 3m
viaBoston(BOS)
DSM→BOS+1h 30mBOS→CHS
5h 15m
viaDenver(DEN)
DSM→DEN+1h 30mDEN→CHS
5h 21m
Search all options on Kiwi.com → Total times include an estimated 90-minute layover. Actual times vary by airline and connection.

Frequently asked questions

Are there direct flights from Des Moines to Charleston? Currently, there are no direct flights from DSM to CHS. You may need to connect through another airport.

Related guides for this route

Sibling pages from across Flightmaps — fares, visa rules, country aggregations, and per-airline routes for Des Moines → Charleston.

Cheap flights from Des Moines to Charleston Cheapest month to fly to Charleston Flights from USA Flights to USA Visa-free with USA passport All airports in USA

Try a nearby airport to Des Moines

Flights to Charleston (CHS) from other airports within 350 km of Des Moines. Often unlocks cheaper fares or better times.

CID → CHS 166 km from DSM Cedar Rapids → Charleston USA · 20 destinations OMA → CHS 190 km from DSM Omaha → Charleston USA · 37 destinations MLI → CHS 262 km from DSM Moline → Charleston USA · 11 destinations MCI → CHS 265 km from DSM Kansas City → Charleston USA · 60 destinations LNK → CHS 271 km from DSM Lincoln → Charleston USA · 9 destinations

Or try a nearby airport to Charleston

Flights from Des Moines (DSM) to other airports within 350 km of Charleston.

DSM → HHH 96 km from CHS Des Moines → Hilton Head USA · 8 destinations DSM → MYR 136 km from CHS Des Moines → Myrtle Beach USA · 60 destinations DSM → SAV 138 km from CHS Des Moines → Savannah USA · 39 destinations DSM → CAE 154 km from CHS Des Moines → Columbia USA · 13 destinations DSM → AGS 188 km from CHS Des Moines → Augusta USA · 7 destinations

Other flights from Des Moines (DSM)

Atlanta (ATL) Austin (AUS) Boston (BOS) Burbank (BUR) Charlotte (CLT) Chicago (ORD) Chicago (MDW) Dallas (DFW) All 35 destinations →

Other flights from Charleston (CHS)

Akron (CAK) Albany (ALB) Atlanta (ATL) Atlantic City (ACY) Austin (AUS) Baltimore (BWI) Boston (BOS) Burlington (BTV) All 55 destinations →