Flights from Santiago to Guayaquil (STI → GYE)

STI
Santiago
Cibao International, Dominican Republic
GYE
Guayaquil
Simon Bolivar International, Ecuador
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No direct flights found. Here are the 5 fastest 1-stop options.
viaPanama City(PTY)
STI→PTY+1h 30mPTY→GYE
4h 43m
viaMiami(MIA)
STI→MIA+1h 30mMIA→GYE
6h 35m
viaFort Lauderdale(FLL)
STI→FLL+1h 30mFLL→GYE
6h 38m
viaNew York(JFK)
STI→JFK+1h 30mJFK→GYE
9h 57m
viaMadrid(MAD)
STI→MAD+1h 30mMAD→GYE
19h 59m
Search all options on Kiwi.com → Total times include an estimated 90-minute layover. Actual times vary by airline and connection.

Frequently asked questions

Are there direct flights from Santiago to Guayaquil? Currently, there are no direct flights from STI to GYE. You may need to connect through another airport.

Related guides for this route

Sibling pages from across Flightmaps — fares, visa rules, country aggregations, and per-airline routes for Santiago → Guayaquil.

Cheap flights from Santiago to Guayaquil Cheapest month to fly to Guayaquil Flights from Dominican Republic Flights to Ecuador Visa-free with Dominican Republic passport All airports in Ecuador

Try a nearby airport to Santiago

Flights to Guayaquil (GYE) from other airports within 350 km of Santiago. Often unlocks cheaper fares or better times.

POP → GYE 39 km from STI Puerto Plata → Guayaquil Dominican Republic · 18 destinations AZS → GYE 92 km from STI El Catey/Samana → Guayaquil Dominican Republic · 5 destinations JBQ → GYE 113 km from STI Santo Domingo → Guayaquil Dominican Republic · 6 destinations SDQ → GYE 146 km from STI Santo Domingo → Guayaquil Dominican Republic · 49 destinations CAP → GYE 171 km from STI Cap Haitien → Guayaquil Haiti · 11 destinations

Or try a nearby airport to Guayaquil

Flights from Santiago (STI) to other airports within 350 km of Guayaquil.

STI → UIO 281 km from GYE Santiago → Quito Ecuador · 24 destinations

Other flights from Santiago (STI)

Boston (BOS) Fort Lauderdale (FLL) Madrid (MAD) Miami (MIA) New York (EWR) New York (JFK) Orlando (MCO) Panama City (PTY) All 11 destinations →

Other flights from Guayaquil (GYE)

Amsterdam (AMS) Bogota (BOG) Buenos Aires (EZE) Cuenca (CUE) Fort Lauderdale (FLL) Galapagos Islands (GPS) Lima (LIM) Madrid (MAD) All 16 destinations →