Flights from Knoxville to Buffalo (TYS → BUF)

TYS
Knoxville
Mc Ghee Tyson, USA
BUF
Buffalo
Buffalo Niagara International, USA
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No direct flights found. Here are the 20 fastest 1-stop options.
viaDetroit(DTW)
TYS→DTW+1h 30mDTW→BUF
2h 47m
viaDulles(IAD)
TYS→IAD+1h 30mIAD→BUF
2h 50m
viaCharlotte(CLT)
TYS→CLT+1h 30mCLT→BUF
2h 52m
viaWashington(DCA)
TYS→DCA+1h 30mDCA→BUF
2h 53m
viaBaltimore(BWI)
TYS→BWI+1h 30mBWI→BUF
2h 55m
viaNashville(BNA)
TYS→BNA+1h 30mBNA→BUF
2h 59m
viaPhiladelphia(PHL)
TYS→PHL+1h 30mPHL→BUF
3h 5m
viaAtlanta(ATL)
TYS→ATL+1h 30mATL→BUF
3h 8m
viaNew York(EWR)
TYS→EWR+1h 30mEWR→BUF
3h 14m
viaChicago(MDW)
TYS→MDW+1h 30mMDW→BUF
3h 15m
viaNew York(LGA)
TYS→LGA+1h 30mLGA→BUF
3h 16m
viaChicago(ORD)
TYS→ORD+1h 30mORD→BUF
3h 18m
viaBoston(BOS)
TYS→BOS+1h 30mBOS→BUF
3h 49m
viaMinneapolis(MSP)
TYS→MSP+1h 30mMSP→BUF
4h 23m
viaOrlando(MCO)
TYS→MCO+1h 30mMCO→BUF
4h 26m
viaTampa(TPA)
TYS→TPA+1h 30mTPA→BUF
4h 32m
viaSarasota(SRQ)
TYS→SRQ+1h 30mSRQ→BUF
4h 41m
viaFort Lauderdale(FLL)
TYS→FLL+1h 30mFLL→BUF
5h 4m
viaMiami(MIA)
TYS→MIA+1h 30mMIA→BUF
5h 7m
viaDallas(DAL)
TYS→DAL+1h 30mDAL→BUF
5h 13m
Search all options on Kiwi.com → Total times include an estimated 90-minute layover. Actual times vary by airline and connection.

Frequently asked questions

Are there direct flights from Knoxville to Buffalo? Currently, there are no direct flights from TYS to BUF. You may need to connect through another airport.

Related guides for this route

Sibling pages from across Flightmaps — fares, visa rules, country aggregations, and per-airline routes for Knoxville → Buffalo.

Cheap flights from Knoxville to Buffalo Cheapest month to fly to Buffalo Flights from USA Flights to USA Visa-free with USA passport All airports in USA

Try a nearby airport to Knoxville

Flights to Buffalo (BUF) from other airports within 350 km of Knoxville. Often unlocks cheaper fares or better times.

AVL → BUF 138 km from TYS Asheville → Buffalo USA · 26 destinations CHA → BUF 139 km from TYS Chattanooga → Buffalo USA · 16 destinations TRI → BUF 161 km from TYS Bristol, VA/Johnson City/Kingsport → Buffalo USA · 8 destinations GSP → BUF 190 km from TYS Greenville → Buffalo USA · 31 destinations ATL → BUF 244 km from TYS Atlanta → Buffalo USA · 246 destinations

Or try a nearby airport to Buffalo

Flights from Knoxville (TYS) to other airports within 350 km of Buffalo.

TYS → ROC 89 km from BUF Knoxville → Rochester USA · 27 destinations TYS → YTZ 94 km from BUF Knoxville → Toronto Canada · 19 destinations TYS → YHM 101 km from BUF Knoxville → Hamilton Canada · 12 destinations TYS → YYZ 109 km from BUF Knoxville → Toronto Canada · 194 destinations TYS → YXU 197 km from BUF Knoxville → London Canada · 6 destinations

Other flights from Knoxville (TYS)

Atlanta (ATL) Austin (AUS) Baltimore (BWI) Baton Rouge (BTR) Bentonville (XNA) Boston (BOS) Charlotte (CLT) Chicago (MDW) All 40 destinations →

Other flights from Buffalo (BUF)

Atlanta (ATL) Baltimore (BWI) Boston (BOS) Charlotte (CLT) Chicago (ORD) Chicago (MDW) Dallas (DFW) Dallas (DAL) All 29 destinations →