Flights from Knoxville to Des Moines (TYS → DSM)

TYS
Knoxville
Mc Ghee Tyson, USA
DSM
Des Moines
Des Moines International, USA
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No direct flights found. Here are the 20 fastest 1-stop options.
viaNashville(BNA)
TYS→BNA+1h 30mBNA→DSM
2h 47m
viaChicago(MDW)
TYS→MDW+1h 30mMDW→DSM
2h 57m
viaChicago(ORD)
TYS→ORD+1h 30mORD→DSM
2h 58m
viaAtlanta(ATL)
TYS→ATL+1h 30mATL→DSM
3h 11m
viaDetroit(DTW)
TYS→DTW+1h 30mDTW→DSM
3h 20m
viaCharlotte(CLT)
TYS→CLT+1h 30mCLT→DSM
3h 22m
viaMinneapolis(MSP)
TYS→MSP+1h 30mMSP→DSM
3h 26m
viaFort Walton Beach(VPS)
TYS→VPS+1h 30mVPS→DSM
3h 53m
viaGulf Shores(GUF)
TYS→GUF+1h 30mGUF→DSM
3h 56m
viaWashington(DCA)
TYS→DCA+1h 30mDCA→DSM
4h 1m
viaDallas(DFW)
TYS→DFW+1h 30mDFW→DSM
4h 8m
viaJacksonville(JAX)
TYS→JAX+1h 30mJAX→DSM
4h 9m
viaPhiladelphia(PHL)
TYS→PHL+1h 30mPHL→DSM
4h 23m
viaHouston(IAH)
TYS→IAH+1h 30mIAH→DSM
4h 29m
viaHouston(HOU)
TYS→HOU+1h 30mHOU→DSM
4h 33m
viaOrlando(SFB)
TYS→SFB+1h 30mSFB→DSM
4h 36m
viaNew York(EWR)
TYS→EWR+1h 30mEWR→DSM
4h 37m
viaNew York(LGA)
TYS→LGA+1h 30mLGA→DSM
4h 40m
viaSaint Petersburg(PIE)
TYS→PIE+1h 30mPIE→DSM
4h 41m
viaAustin(AUS)
TYS→AUS+1h 30mAUS→DSM
4h 43m
Search all options on Kiwi.com → Total times include an estimated 90-minute layover. Actual times vary by airline and connection.

Frequently asked questions

Are there direct flights from Knoxville to Des Moines? Currently, there are no direct flights from TYS to DSM. You may need to connect through another airport.

Related guides for this route

Sibling pages from across Flightmaps — fares, visa rules, country aggregations, and per-airline routes for Knoxville → Des Moines.

Cheap flights from Knoxville to Des Moines Cheapest month to fly to Des Moines Flights from USA Flights to USA Visa-free with USA passport All airports in USA

Try a nearby airport to Knoxville

Flights to Des Moines (DSM) from other airports within 350 km of Knoxville. Often unlocks cheaper fares or better times.

AVL → DSM 138 km from TYS Asheville → Des Moines USA · 26 destinations CHA → DSM 139 km from TYS Chattanooga → Des Moines USA · 16 destinations TRI → DSM 161 km from TYS Bristol, VA/Johnson City/Kingsport → Des Moines USA · 8 destinations GSP → DSM 190 km from TYS Greenville → Des Moines USA · 31 destinations ATL → DSM 244 km from TYS Atlanta → Des Moines USA · 246 destinations

Or try a nearby airport to Des Moines

Flights from Knoxville (TYS) to other airports within 350 km of Des Moines.

TYS → CID 166 km from DSM Knoxville → Cedar Rapids USA · 20 destinations TYS → OMA 190 km from DSM Knoxville → Omaha USA · 37 destinations TYS → MLI 262 km from DSM Knoxville → Moline USA · 11 destinations TYS → MCI 265 km from DSM Knoxville → Kansas City USA · 60 destinations TYS → LNK 271 km from DSM Knoxville → Lincoln USA · 9 destinations

Other flights from Knoxville (TYS)

Atlanta (ATL) Austin (AUS) Baltimore (BWI) Baton Rouge (BTR) Bentonville (XNA) Boston (BOS) Charlotte (CLT) Chicago (MDW) All 40 destinations →

Other flights from Des Moines (DSM)

Atlanta (ATL) Austin (AUS) Boston (BOS) Burbank (BUR) Charlotte (CLT) Chicago (ORD) Chicago (MDW) Dallas (DFW) All 35 destinations →